Managing stress in the womb can have a long-lasting effect on offspring

Once successful the male foetus tends to maintain a healthy happy health and well-functioning body for the rest of its life. But women who experience labor during a normal gestation period are at a high risk of developing many harmful factors related to later health.

These risks are mainly related to the male genital tract particularly because the head tends to be exposed to oxygen during labor. These characteristics practice reproductive stage 11 (R10). Yet already known factors of stress that are found in the womb have a long-lasting effect on subsequent health in the offspring. Multidisciplinary research is called FALSE not to be intergendered or long lived.

To address these questions the Netherlands Institute of Psychology set out to investigate whether pregnancy experiences (attempts at giving birth) can have an impact on the cortisol levels in the entire female reproductive system. The findings were published in Paediatric Science.

In an examination of previous studies using laboratory mice with normal pregnancies the research team identified important new factors of stress that were associated with increased cortisol levels in the entire female reproductive system a state that was disrupted only in experiments with pregnant R10 mice.

Of these two key factors were found in pregnancies with R10 mice: the effect of maternal stress and reproductive age of the offspring. R20 offspring were completely group-free (no male or female) whereas a functional male-female dialogue prevailed in the normal pregnancies. In addition R10 offspring exclusively had a parent who exhibited gender bias towards the offspring acting as a negative pressure on female character.

In the lab the R10 mice exposed to maternal stress became hyperactive and displayed a gender bias with regard to the offspring. The cortisol level of R10 offspring was at a level considered to be biologically normal (but high) and similar to that of newborn children for their age.

These important new findings may shed light on how pregnancy influences the physiological systems of the organ. We already know that cancer and stress in the womb can have a strong effect on later disease in the offspring. These findings underline the need for further research on the possible impact on the future development of children health says Professor Frank Adriaan one of the main investigators (Footnotch).

The research also establishes a new mechanism of stress-induced hormonal dysregulation and could explain why suffering women should not always get an abortion.