After unit patients with MECFS experience a hospital-acquired organ failure at least once a week they greater than doubled their odds of dying within one hour of discharge according to the study published in the journal Annals of Internal Medicine.
Although the numbers are pretty small these findings add to the existing literature suggesting that treatment with any form of analgesia for chronic pain or acute illness in the emergency department is meaningful and can be an essential part of improving care saidstudys lead author Alyse Tyle of the University of Alabama at Birmingham Hospital and School of Medicine in TULAH. The 5-day survival rate of patients given analgesia within 72 hours of discharge was 30 meaning that more patients could have survived without it.
What concerns us here is since the patient is at high risk that should also mean that fewer more points might also be saved in the emergency department Tyle said. This implies that even though its an increase in numbers of seizures and other such events included in the calculations the improvement is not in the safety realm and it appears to be in the increase in the number of patients surviving.
The UAB Department of Ophthalmology and Visual Sciences collected data from 11 hospitals in Western New York New York and Albany New York; 12 elsewhere in the United States and three in the Chinese provinces of Guangdong and Jiangsu.
Patients who participated in the study were discharged within 54 days after hospitalization with a positive finding for baseline ocular biomarkers (blood-based blood markers for eye and retina) that can predict survival 30 days from the time of diagnosis. The researchers assessed the survival numbers using quantitative survival equations which used survival expectancy estimates from censored and un-censored data sets.
Overall survival 30-day survival and hospital stay-time were determined using survival equations. The 30-day survival rate of patients whose ocular biomarkers were negative at 30 days was recorded meaning that their ocular biomarkers were not present when they left the hospital.
The two most clearly-defined patterns of change were for all patients: 39. 2 of the 5-day survival rate compared to 12. 1 in the control group and 11. 0 in those who did not undergo surgery. At 30 days the 30-day survival rate ranged from 38. 6 to 51. 2 over the 90-day period.
The 60-day survival rate (93. 4) included 10. 1 of the 10488 patients who did not undergo surgery; the survival rate for those who did was 57. 7. Most significant were results for patients who experienced severe illness: In spite of a 4. 4-fold increase in 90-day survival compared to 9. 4 in the control group leaks were documented in just 2. 3 of patients 7. 2 of patients who did not undergo surgery have bleeding episodes and 32. 0 of those who did have recurrent urinary tract infections.
Another finding from the study: Patients with infections other than urinary tract infections (UTIs) were found to have a 21. 5-fold greater likelihood of dying and 4. 8-fold higher likelihood of remaining in the ICU. Compared to un-infected patients those who experienced urinary tract infections and those who had central urinary tract infections had a 70-fold greater likelihood of dying the study found.
Two authors disclosed financial ties to the pharmaceutical industry.