Insulin oligosaccharides affect heart function in Type 1 diabetes

INSULRIA OCH publishes an article in CNS Function titled Replenishing insulin oligosaccharides ameliorate impaired cardiac function in patients with type 1 diabetes using a simple high-fat series of trials on 18 subjects that reports a response of healthy human subjects to a high-fat high-cholesterol diet. Insulin oligosaccharides (HOPs) are polysaccharides present in the human body that are involved in digestion and the conversion of dietary carbohydrates into energy. HOPs are found in many fruits and vegetables including asparagus cherries strawberries bran and cranberries. High amounts of fructose are part of the American diet and increased consumption of fruit and vegetables therefore has been linked to a high prevalence of obesity and diabetes. In type 1 diabetes insulin levels in blood reach insulin resistance i.e. their ability to more effectively convert sugars into energy therefore leading to an impaired ability to sustain glucose production in the body. FIGURE Graphical analysis of HOPs measured from liver samples of healthy volunteers in-depth. Image courtesy of CNS Function. The men in this trial were randomized to a high-altitude treadmill test (HVT) or a low-altitude treadmill test ( LNT) to determine the linearity of their heart rate and the amplitude of their heart Lung output was determined in accordance with the Swiss Heart Lung Test () which is a diagnostic tool for Type 1 diabetes Body oxygen uptake was measured in a chest x-ray and an electrocardiogram scan performed on each subject while the average left ventricular ejection fraction and ejection fraction with aortic aventriculate arteries were also monitored. The idea of precovery – bearing a summary of the prior results albeit one that represents the hypothesis – is to determine after a course of treatment whether insulin oligosaccharides can be used to prevent worsening of type 1 diabetes and allow sticking with the diet. That is isolation from the diet is not necessary to achieve high blood insulin levels and therefore the prospective exercise training can be conducted with acceptable safety reports Dr. Sefaroli. FIGURE Graphical analysis of HOPs measured from liver samples of healthy volunteers in-depth. Image courtesy of CNS Function.